That's the view of former Arsenal midfielder-turned-pundit Paul Merson.
The Southampton ace has been linked with a move to Liverpool over the last week with Jurgen Klopp keen to strengthen his defence.
Manchester United and Manchester City are both said to be keen on making a move for the former Celtic man too however, with Jose Mourinho a big fan and Pep Guardiola seeing him as as Vincent Kompany's replacement.
Liverpool sit second in the table after a strong start, but conceding goals has been a problem for Klopp's men.
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If they can go out and get Van Dijk, I think £50 million, that nearly wins you the Premier League
Paul Merson
And Merson reckons the Reds should go all out for the Dutchman if they want to be lifting the Premier League trophy in May.
“For me, I think if Liverpool get together and go and buy Van Dijk for £50 million in January, they will take some beating," Merson told talkSPORT.
“They’ve got the firepower going forward, I just don’t think they’ve got it at the back.
“I know they’ve done it this season so far, but defensively they aren’t going to be good enough [against the big teams].
“But if they can go out and get Van Dijk, I think £50 million, that nearly wins you the Premier League.”
Liverpool will be hoping to close the gap on leaders Chelsea when they take on Bournemouth on Sunday (1.30pm).